| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| leuB | leuC | Rta_28170 | Rta_15480 | Candidate 3-isopropylmalate dehydrogenase (Beta-IPM dehydrogenase); Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | Alpha-IPM isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.958 |
| leuB | leuC-2 | Rta_28170 | Rta_18460 | Candidate 3-isopropylmalate dehydrogenase (Beta-IPM dehydrogenase); Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | Alpha-IPM isomerase. | 0.981 |
| leuB | leuC-3 | Rta_28170 | Rta_21660 | Candidate 3-isopropylmalate dehydrogenase (Beta-IPM dehydrogenase); Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | Alpha-IPM isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.944 |
| leuB | leuC-4 | Rta_28170 | Rta_28150 | Candidate 3-isopropylmalate dehydrogenase (Beta-IPM dehydrogenase); Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | Candidate 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.975 |
| leuB | leuC-5 | Rta_28170 | Rta_29310 | Candidate 3-isopropylmalate dehydrogenase (Beta-IPM dehydrogenase); Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | Alpha-IPM isomerase. | 0.945 |
| leuB | leuD | Rta_28170 | Rta_15475 | Candidate 3-isopropylmalate dehydrogenase (Beta-IPM dehydrogenase); Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | Alpha-IPM isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.943 |
| leuB | leuD-2 | Rta_28170 | Rta_18450 | Candidate 3-isopropylmalate dehydrogenase (Beta-IPM dehydrogenase); Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | Alpha-IPM isomerase; Belongs to the LeuD family. | 0.930 |
| leuB | leuD-3 | Rta_28170 | Rta_21650 | Candidate 3-isopropylmalate dehydrogenase (Beta-IPM dehydrogenase); Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | Alpha-IPM isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.944 |
| leuB | leuD-4 | Rta_28170 | Rta_28160 | Candidate 3-isopropylmalate dehydrogenase (Beta-IPM dehydrogenase); Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | Candidate 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.979 |
| leuB | leuD-5 | Rta_28170 | Rta_29300 | Candidate 3-isopropylmalate dehydrogenase (Beta-IPM dehydrogenase); Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | Alpha-IPM isomerase; Belongs to the LeuD family. | 0.917 |
| leuC | leuB | Rta_15480 | Rta_28170 | Alpha-IPM isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | Candidate 3-isopropylmalate dehydrogenase (Beta-IPM dehydrogenase); Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.958 |
| leuC | leuC-2 | Rta_15480 | Rta_18460 | Alpha-IPM isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | Alpha-IPM isomerase. | 0.910 |
| leuC | leuC-3 | Rta_15480 | Rta_21660 | Alpha-IPM isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | Alpha-IPM isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.903 |
| leuC | leuC-4 | Rta_15480 | Rta_28150 | Alpha-IPM isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | Candidate 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.902 |
| leuC | leuC-5 | Rta_15480 | Rta_29310 | Alpha-IPM isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | Alpha-IPM isomerase. | 0.906 |
| leuC | leuD | Rta_15480 | Rta_15475 | Alpha-IPM isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | Alpha-IPM isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.999 |
| leuC | leuD-2 | Rta_15480 | Rta_18450 | Alpha-IPM isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | Alpha-IPM isomerase; Belongs to the LeuD family. | 0.958 |
| leuC | leuD-3 | Rta_15480 | Rta_21650 | Alpha-IPM isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | Alpha-IPM isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.998 |
| leuC | leuD-4 | Rta_15480 | Rta_28160 | Alpha-IPM isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | Candidate 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.995 |
| leuC | leuD-5 | Rta_15480 | Rta_29300 | Alpha-IPM isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | Alpha-IPM isomerase; Belongs to the LeuD family. | 0.956 |