Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hemHHeme synthetase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (367 aa)    
Predicted Functional Partners:
Rta_03160
Candidate membrane protein.
 
  
 0.947
ctaB
Candidate protoheme IX farnesyltransferase (Heme O synthase), membrane protein; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
     
 0.929
bfr
Candidate bacterioferritin; Iron-storage protein.
     
 0.917
hemE
Candidate Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.895
hemC
Pre-uroporphyrinogen synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.858
cyaY
Candidate iron binding protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
    
 
 0.800
hemF
Coprogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
 
  
 0.733
hemB
Candidate Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
  
 0.607
Rta_15710
Hydrolases (HAD superfamily)-like protein.
       0.604
Rta_09310
ATP-binding cassette, subfamily B, bacterial; Candidate ABC type transport system involved in Fe S cluster assembly, permease and ATPase components.
   
 
 0.586
Your Current Organism:
Ramlibacter tataouinensis
NCBI taxonomy Id: 365046
Other names: Acidivorax sp. TTB310, Acidovorax sp. TTB310, R. tataouinensis TTB310, Ramlibacter tataouinensis TTB310, Ramlibacter tataouinensis str. TTB310, Ramlibacter tataouinensis strain TTB310
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