Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fumCCandidate fumarate hydratase class II (Fumarase C); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (459 aa)    
Predicted Functional Partners:
sdhA
Candidate succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.990
mdh
Candidate malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.985
fumA
Candidate fumarate hydratase class I (Fumarase); Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.981
gltA
Candidate citrate synthase; Belongs to the citrate synthase family.
   
 0.978
Rta_37850
Bifunctional protein : malic enzyme; phosphate acetyltransferase (phosphotransacetylase)-like protein; Belongs to the malic enzymes family.
  
 
 0.976
Rta_28080
Succinate dehydrogenase cytochrome b-556 subunit-like protein.
   
 
 0.954
sdhB
Candidate succinate dehydrogenase iron-sulfur protein.
  
 0.952
sdhB-2
Candidate succinate dehydrogenase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.952
Rta_30600
Formate dehydrogenase beta subunit; NADH:ubiquinone oxidoreductase subunit 2 or 24 kDa subunit and subunit 1 or 51 kDa subunit fusion, chain E and chain F fusion-like protein.
   
 0.943
acnA
Candidate aconitase (aconitate hydratase).
  
 0.939
Your Current Organism:
Ramlibacter tataouinensis
NCBI taxonomy Id: 365046
Other names: Acidivorax sp. TTB310, Acidovorax sp. TTB310, R. tataouinensis TTB310, Ramlibacter tataouinensis TTB310, Ramlibacter tataouinensis str. TTB310, Ramlibacter tataouinensis strain TTB310
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