Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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acsACandidate acetyl-coenzyme A synthetase(Acetate--CoA ligase); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (661 aa)    
Predicted Functional Partners:
gltA
Candidate citrate synthase; Belongs to the citrate synthase family.
  
 0.933
glcB
Candidate Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 0.925
Rta_10430
Acetyl-CoA synthase (Acetate thiokinase).
  
  
 
0.923
accC
Candidate Biotin carboxylase (subunit of acetyl-CoA carboxylase); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.918
Rta_05680
Acetyl-CoA C-acetyltransferase-like protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.917
Rta_18100
Acetyl-CoA C-acetyltransferase-like protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.917
Rta_20040
3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.917
Rta_18250
Candidate propionyl-CoA carboxylase.
  
 0.913
Rta_02980
Candidate NAD-dependent aldehyde dehydrogenase.
   
 0.911
accA-2
Candidate Acetyl or propionyl-CoA carboxylase subunit.
  
 0.911
Your Current Organism:
Ramlibacter tataouinensis
NCBI taxonomy Id: 365046
Other names: Acidivorax sp. TTB310, Acidovorax sp. TTB310, R. tataouinensis TTB310, Ramlibacter tataouinensis TTB310, Ramlibacter tataouinensis str. TTB310, Ramlibacter tataouinensis strain TTB310
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