| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| alaS | guaA | Rta_15010 | Rta_19730 | Candidate alanyl-tRNA synthetase (Alanine--tRNA ligase); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Candidate GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.663 |
| alaS | ileS | Rta_15010 | Rta_31790 | Candidate alanyl-tRNA synthetase (Alanine--tRNA ligase); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Candidate isoleucyl-tRNA synthetase (Isoleucine--tRNA ligase); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 sub [...] | 0.817 |
| alaS | leuS | Rta_15010 | Rta_02310 | Candidate alanyl-tRNA synthetase (Alanine--tRNA ligase); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Candidate Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.869 |
| alaS | pheS | Rta_15010 | Rta_17810 | Candidate alanyl-tRNA synthetase (Alanine--tRNA ligase); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Candidate phenylalanyl-tRNA synthetase alpha subunit(Phenylalanine--tRNA ligase alpha subunit); Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.513 |
| alaS | pheT | Rta_15010 | Rta_17820 | Candidate alanyl-tRNA synthetase (Alanine--tRNA ligase); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Candidate phenylalanyl-tRNA synthetase beta subunit(Phenylalanine--tRNA ligase alpha subuniit); Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.918 |
| alaS | purL | Rta_15010 | Rta_20330 | Candidate alanyl-tRNA synthetase (Alanine--tRNA ligase); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Candidate phosphoribosylformylglycinamidine synthase (FGAM synthase); Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.783 |
| alaS | rpoB | Rta_15010 | Rta_35690 | Candidate alanyl-tRNA synthetase (Alanine--tRNA ligase); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Candidate DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.581 |
| alaS | thrS | Rta_15010 | Rta_17770 | Candidate alanyl-tRNA synthetase (Alanine--tRNA ligase); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Candidate threonyl-tRNA synthetase (Threonine--tRNA ligase); Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). | 0.854 |
| alaS | tyrS | Rta_15010 | Rta_07080 | Candidate alanyl-tRNA synthetase (Alanine--tRNA ligase); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Candidate Tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. | 0.525 |
| guaA | alaS | Rta_19730 | Rta_15010 | Candidate GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Candidate alanyl-tRNA synthetase (Alanine--tRNA ligase); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.663 |
| guaA | ileS | Rta_19730 | Rta_31790 | Candidate GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Candidate isoleucyl-tRNA synthetase (Isoleucine--tRNA ligase); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 sub [...] | 0.735 |
| guaA | leuS | Rta_19730 | Rta_02310 | Candidate GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Candidate Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.520 |
| guaA | pheS | Rta_19730 | Rta_17810 | Candidate GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Candidate phenylalanyl-tRNA synthetase alpha subunit(Phenylalanine--tRNA ligase alpha subunit); Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.560 |
| guaA | pheT | Rta_19730 | Rta_17820 | Candidate GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Candidate phenylalanyl-tRNA synthetase beta subunit(Phenylalanine--tRNA ligase alpha subuniit); Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.865 |
| guaA | purL | Rta_19730 | Rta_20330 | Candidate GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Candidate phosphoribosylformylglycinamidine synthase (FGAM synthase); Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.972 |
| guaA | rplT | Rta_19730 | Rta_17800 | Candidate GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Candidate 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.538 |
| guaA | rpoB | Rta_19730 | Rta_35690 | Candidate GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Candidate DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.887 |
| guaA | thrS | Rta_19730 | Rta_17770 | Candidate GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Candidate threonyl-tRNA synthetase (Threonine--tRNA ligase); Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). | 0.578 |
| ileS | alaS | Rta_31790 | Rta_15010 | Candidate isoleucyl-tRNA synthetase (Isoleucine--tRNA ligase); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 sub [...] | Candidate alanyl-tRNA synthetase (Alanine--tRNA ligase); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.817 |
| ileS | guaA | Rta_31790 | Rta_19730 | Candidate isoleucyl-tRNA synthetase (Isoleucine--tRNA ligase); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 sub [...] | Candidate GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.735 |