Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cobBNAD-dependent protein deacetylase, SIR2 family-like protein; Belongs to the sirtuin family. Class III subfamily. (245 aa)    
Predicted Functional Partners:
Rta_15950
(NAD(+) diphosphorylase) (NMN adenylyltransferase); ADP compounds hydrolase.
  
 
  0.967
nadE
Candidate NAD(+) synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.951
nadD
Candidate nicotinate-nucleotide adenylyltransferase (Deamido-NAD(+) pyrophosphorylase); Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.934
ppnK
Candidate inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase); Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.916
pntA
Candidate NAD(P) transhydrogenase subunit alpha part 1.
     
 0.905
pntAb
Candidate NAD(P) transhydrogenase subunit alpha part2.
     
 0.904
pntB
Candidate NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
    
  0.901
rlmB
Candidate 23S rRNA (guanosine-2'-O-)-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA.
  
    0.796
Rta_12550
Hypothetical protein.
   
   0.795
Rta_37520
Proteins containing SET domain-like protein.
    
 0.737
Your Current Organism:
Ramlibacter tataouinensis
NCBI taxonomy Id: 365046
Other names: Acidivorax sp. TTB310, Acidovorax sp. TTB310, R. tataouinensis TTB310, Ramlibacter tataouinensis TTB310, Ramlibacter tataouinensis str. TTB310, Ramlibacter tataouinensis strain TTB310
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