STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rta_23720Acetolactate synthase large subunit (Acetohydroxy-acid synthase large subunit)-like protein; Belongs to the TPP enzyme family. (544 aa)    
Predicted Functional Partners:
ilvH
Candidate acetolactate synthase small subunit (Acetohydroxy-acid synthase small subunit).
 
 0.989
ilvC
Alpha-keto-beta-hydroxylacil reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
 0.972
ttuC
Candidate Tartrate dehydrogenase.
  
 0.930
Rta_15910
3-isopropylmalate dehydrogenase (Beta-IPM dehydrogenase)-like protein.
  
 0.930
Rta_24470
Candidate tartrate dehydrogenase.
  
 0.930
leuB
Candidate 3-isopropylmalate dehydrogenase (Beta-IPM dehydrogenase); Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
  
 0.930
Rta_14300
Acetolactate synthase large subunit (Acetohydroxy-acid synthase large subunit)-like protein; Belongs to the TPP enzyme family.
  
  
 
0.926
ilvI
Candidate acetolactate synthase large subunit (Acetohydroxy-acid synthase large subunit).
  
  
 
0.925
Rta_16710
Acetohydroxy-acid synthase small subunit; Belongs to the TPP enzyme family.
  
  
  0.914
Rta_37850
Bifunctional protein : malic enzyme; phosphate acetyltransferase (phosphotransacetylase)-like protein; Belongs to the malic enzymes family.
  
 
 0.900
Your Current Organism:
Ramlibacter tataouinensis
NCBI taxonomy Id: 365046
Other names: Acidivorax sp. TTB310, Acidovorax sp. TTB310, R. tataouinensis TTB310, Ramlibacter tataouinensis TTB310, Ramlibacter tataouinensis str. TTB310, Ramlibacter tataouinensis strain TTB310
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