| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rta_05500 | kynA | Rta_05500 | Rta_27930 | Candidate 4-hydroxyphenylpyruvate dioxygenase. | Vermilion protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.577 |
| Rta_18140 | Rta_18170 | Rta_18140 | Rta_18170 | Oxidoreductases-like protein. | Conserved hypothetical protein. | 0.951 |
| Rta_18140 | Rta_35050 | Rta_18140 | Rta_35050 | Oxidoreductases-like protein. | Candidate 2-aminobenzoate-CoA ligase. | 0.979 |
| Rta_18140 | kynA | Rta_18140 | Rta_27930 | Oxidoreductases-like protein. | Vermilion protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.633 |
| Rta_18140 | kynU | Rta_18140 | Rta_27920 | Oxidoreductases-like protein. | Kynureninase (L-kynurenine hydrolase)-like protein; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.462 |
| Rta_18170 | Rta_18140 | Rta_18170 | Rta_18140 | Conserved hypothetical protein. | Oxidoreductases-like protein. | 0.951 |
| Rta_18170 | Rta_35050 | Rta_18170 | Rta_35050 | Conserved hypothetical protein. | Candidate 2-aminobenzoate-CoA ligase. | 0.767 |
| Rta_18170 | kynA | Rta_18170 | Rta_27930 | Conserved hypothetical protein. | Vermilion protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.414 |
| Rta_21145 | kynA | Rta_21145 | Rta_27930 | Candidate septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Vermilion protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.709 |
| Rta_35050 | Rta_18140 | Rta_35050 | Rta_18140 | Candidate 2-aminobenzoate-CoA ligase. | Oxidoreductases-like protein. | 0.979 |
| Rta_35050 | Rta_18170 | Rta_35050 | Rta_18170 | Candidate 2-aminobenzoate-CoA ligase. | Conserved hypothetical protein. | 0.767 |
| Rta_35050 | kynA | Rta_35050 | Rta_27930 | Candidate 2-aminobenzoate-CoA ligase. | Vermilion protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.483 |
| kynA | Rta_05500 | Rta_27930 | Rta_05500 | Vermilion protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Candidate 4-hydroxyphenylpyruvate dioxygenase. | 0.577 |
| kynA | Rta_18140 | Rta_27930 | Rta_18140 | Vermilion protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Oxidoreductases-like protein. | 0.633 |
| kynA | Rta_18170 | Rta_27930 | Rta_18170 | Vermilion protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Conserved hypothetical protein. | 0.414 |
| kynA | Rta_21145 | Rta_27930 | Rta_21145 | Vermilion protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Candidate septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.709 |
| kynA | Rta_35050 | Rta_27930 | Rta_35050 | Vermilion protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Candidate 2-aminobenzoate-CoA ligase. | 0.483 |
| kynA | kynB | Rta_27930 | Rta_27910 | Vermilion protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Conserved hypothetical protein; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | 0.994 |
| kynA | kynU | Rta_27930 | Rta_27920 | Vermilion protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Kynureninase (L-kynurenine hydrolase)-like protein; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.998 |
| kynA | trpA | Rta_27930 | Rta_28230 | Vermilion protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Candidate tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.808 |