Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
acnACandidate aconitase (aconitate hydratase). (952 aa)    
Predicted Functional Partners:
gltA
Candidate citrate synthase; Belongs to the citrate synthase family.
 
 0.998
icdA
Candidate isocitrate dehydrogenase [NADP] (Oxalosuccinate decarboxylase).
 
 0.994
Rta_12490
Conserved hypothetical protein.
  
 
 0.985
fumC
Candidate fumarate hydratase class II (Fumarase C); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.939
acnB
Aconitase 2; Belongs to the aconitase/IPM isomerase family.
    
 0.937
aceA
Isocitratase.
   
 
 0.932
mdh
Candidate malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.928
sodB
Candidate superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.845
sucA
Candidate 2-oxoglutarate dehydrogenase E1 component (Alpha- ketoglutarate dehydrogenase).
 
 0.829
rpmF
Candidate 50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
   
 0.816
Your Current Organism:
Ramlibacter tataouinensis
NCBI taxonomy Id: 365046
Other names: Acidivorax sp. TTB310, Acidovorax sp. TTB310, R. tataouinensis TTB310, Ramlibacter tataouinensis TTB310, Ramlibacter tataouinensis str. TTB310, Ramlibacter tataouinensis strain TTB310
Server load: low (28%) [HD]