Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
acnBAconitase 2; Belongs to the aconitase/IPM isomerase family. (861 aa)    
Predicted Functional Partners:
icdA
Candidate isocitrate dehydrogenase [NADP] (Oxalosuccinate decarboxylase).
  
 
 0.980
gltA
Candidate citrate synthase; Belongs to the citrate synthase family.
  
 
 0.971
acnA
Candidate aconitase (aconitate hydratase).
    
 0.937
mdh
Candidate malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
  
 0.922
aceA
Isocitratase.
   
 
 0.915
Rta_12490
Conserved hypothetical protein.
    
 0.913
sucA
Candidate 2-oxoglutarate dehydrogenase E1 component (Alpha- ketoglutarate dehydrogenase).
   
  
 0.846
fumA
Candidate fumarate hydratase class I (Fumarase); Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.840
sucC
Candidate succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
  
 0.840
Rta_28080
Succinate dehydrogenase cytochrome b-556 subunit-like protein.
  
  
 0.720
Your Current Organism:
Ramlibacter tataouinensis
NCBI taxonomy Id: 365046
Other names: Acidivorax sp. TTB310, Acidovorax sp. TTB310, R. tataouinensis TTB310, Ramlibacter tataouinensis TTB310, Ramlibacter tataouinensis str. TTB310, Ramlibacter tataouinensis strain TTB310
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