| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rta_15900 | pdxA | Rta_15900 | Rta_08400 | 4-phospho-D-threonate 3-dehydrogenase / 4-phospho-D-erythronate 3-dehydrogenase; 4-hydroxythreonine-4-phosphate dehydrogenase (4- (phosphohydroxy)-L-threonine dehydrogenase)-like protein; Belongs to the PdxA family. | Candidate 4-hydroxythreonine-4-phosphate dehydrogenase 2; Belongs to the PdxA family. | 0.917 |
| Rta_15900 | pdxJ | Rta_15900 | Rta_28380 | 4-phospho-D-threonate 3-dehydrogenase / 4-phospho-D-erythronate 3-dehydrogenase; 4-hydroxythreonine-4-phosphate dehydrogenase (4- (phosphohydroxy)-L-threonine dehydrogenase)-like protein; Belongs to the PdxA family. | Candidate pyridoxal phosphate biosynthetic protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.818 |
| Rta_16730 | pdxJ | Rta_16730 | Rta_28380 | 4-hydroxythreonine-4-phosphate dehydrogenase (4- (phosphohydroxy)-L-threonine dehydrogenase)-like protein; Belongs to the PdxA family. | Candidate pyridoxal phosphate biosynthetic protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.833 |
| acpS | era | Rta_28370 | Rta_28400 | 4-phosphopantetheinyltransferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | Candidate GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.835 |
| acpS | lepB | Rta_28370 | Rta_28430 | 4-phosphopantetheinyltransferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | Candidate signal peptidase I (Leader peptidase I); Belongs to the peptidase S26 family. | 0.810 |
| acpS | nagZ | Rta_28370 | Rta_28360 | 4-phosphopantetheinyltransferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | Candidate b-N-acetylhexosaminidase, Glycoside Hydrolase Family 3; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.835 |
| acpS | pdxJ | Rta_28370 | Rta_28380 | 4-phosphopantetheinyltransferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | Candidate pyridoxal phosphate biosynthetic protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.849 |
| acpS | recO | Rta_28370 | Rta_28390 | 4-phosphopantetheinyltransferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | Candidate DNA repair protein; Involved in DNA repair and RecF pathway recombination. | 0.857 |
| acpS | rnc | Rta_28370 | Rta_28410 | 4-phosphopantetheinyltransferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | Candidate ribonuclease III (RNase III); Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.857 |
| era | acpS | Rta_28400 | Rta_28370 | Candidate GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 4-phosphopantetheinyltransferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | 0.835 |
| era | lepB | Rta_28400 | Rta_28430 | Candidate GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Candidate signal peptidase I (Leader peptidase I); Belongs to the peptidase S26 family. | 0.821 |
| era | nagZ | Rta_28400 | Rta_28360 | Candidate GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Candidate b-N-acetylhexosaminidase, Glycoside Hydrolase Family 3; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.835 |
| era | pdxJ | Rta_28400 | Rta_28380 | Candidate GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Candidate pyridoxal phosphate biosynthetic protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.883 |
| era | recO | Rta_28400 | Rta_28390 | Candidate GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Candidate DNA repair protein; Involved in DNA repair and RecF pathway recombination. | 0.926 |
| era | rnc | Rta_28400 | Rta_28410 | Candidate GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Candidate ribonuclease III (RNase III); Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.914 |
| lepB | acpS | Rta_28430 | Rta_28370 | Candidate signal peptidase I (Leader peptidase I); Belongs to the peptidase S26 family. | 4-phosphopantetheinyltransferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | 0.810 |
| lepB | era | Rta_28430 | Rta_28400 | Candidate signal peptidase I (Leader peptidase I); Belongs to the peptidase S26 family. | Candidate GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.821 |
| lepB | nagZ | Rta_28430 | Rta_28360 | Candidate signal peptidase I (Leader peptidase I); Belongs to the peptidase S26 family. | Candidate b-N-acetylhexosaminidase, Glycoside Hydrolase Family 3; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.829 |
| lepB | pdxJ | Rta_28430 | Rta_28380 | Candidate signal peptidase I (Leader peptidase I); Belongs to the peptidase S26 family. | Candidate pyridoxal phosphate biosynthetic protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.792 |
| lepB | recO | Rta_28430 | Rta_28390 | Candidate signal peptidase I (Leader peptidase I); Belongs to the peptidase S26 family. | Candidate DNA repair protein; Involved in DNA repair and RecF pathway recombination. | 0.791 |