| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rta_16570 | Rta_28350 | Rta_16570 | Rta_28350 | Hypothetical protein. | Chaperone protein-like protein. | 0.865 |
| Rta_16570 | dnaK | Rta_16570 | Rta_25080 | Hypothetical protein. | Candidate heat shock protein, HSP70 family; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.935 |
| Rta_16570 | groL | Rta_16570 | Rta_35150 | Hypothetical protein. | groEL protein; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.868 |
| Rta_16570 | groS | Rta_16570 | Rta_35140 | Hypothetical protein. | groES protein; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.702 |
| Rta_16570 | grpE | Rta_16570 | Rta_25070 | Hypothetical protein. | Candidate heat shock protein, HSP70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. S [...] | 0.923 |
| Rta_16570 | hrcA | Rta_16570 | Rta_33180 | Hypothetical protein. | Candidate transcriptional regulator HrcA (Heat-inducible transcription repressor hrcA), HrcA family; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.698 |
| Rta_28350 | Rta_16570 | Rta_28350 | Rta_16570 | Chaperone protein-like protein. | Hypothetical protein. | 0.865 |
| Rta_28350 | dnaJ | Rta_28350 | Rta_25090 | Chaperone protein-like protein. | Candidate heat shock protein J; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | 0.865 |
| Rta_28350 | groL | Rta_28350 | Rta_35150 | Chaperone protein-like protein. | groEL protein; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.906 |
| Rta_28350 | groS | Rta_28350 | Rta_35140 | Chaperone protein-like protein. | groES protein; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.850 |
| Rta_28350 | grpE | Rta_28350 | Rta_25070 | Chaperone protein-like protein. | Candidate heat shock protein, HSP70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. S [...] | 0.934 |
| Rta_28350 | hrcA | Rta_28350 | Rta_33180 | Chaperone protein-like protein. | Candidate transcriptional regulator HrcA (Heat-inducible transcription repressor hrcA), HrcA family; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.491 |
| Rta_33210 | hrcA | Rta_33210 | Rta_33180 | P-loop-containing kinase-like protein; Displays ATPase and GTPase activities. | Candidate transcriptional regulator HrcA (Heat-inducible transcription repressor hrcA), HrcA family; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.732 |
| Rta_33210 | ppnK | Rta_33210 | Rta_33190 | P-loop-containing kinase-like protein; Displays ATPase and GTPase activities. | Candidate inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase); Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.835 |
| Rta_33210 | recN | Rta_33210 | Rta_33200 | P-loop-containing kinase-like protein; Displays ATPase and GTPase activities. | Candidate DNA repair ATPase; May be involved in recombinational repair of damaged DNA. | 0.856 |
| dnaJ | Rta_28350 | Rta_25090 | Rta_28350 | Candidate heat shock protein J; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | Chaperone protein-like protein. | 0.865 |
| dnaJ | dnaK | Rta_25090 | Rta_25080 | Candidate heat shock protein J; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | Candidate heat shock protein, HSP70 family; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.997 |
| dnaJ | groL | Rta_25090 | Rta_35150 | Candidate heat shock protein J; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | groEL protein; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.936 |
| dnaJ | groS | Rta_25090 | Rta_35140 | Candidate heat shock protein J; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | groES protein; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.821 |
| dnaJ | grpE | Rta_25090 | Rta_25070 | Candidate heat shock protein J; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | Candidate heat shock protein, HSP70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. S [...] | 0.985 |
