| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rta_15950 | cobB | Rta_15950 | Rta_19190 | (NAD(+) diphosphorylase) (NMN adenylyltransferase); ADP compounds hydrolase. | NAD-dependent protein deacetylase, SIR2 family-like protein; Belongs to the sirtuin family. Class III subfamily. | 0.967 |
| Rta_15950 | nadD | Rta_15950 | Rta_21170 | (NAD(+) diphosphorylase) (NMN adenylyltransferase); ADP compounds hydrolase. | Candidate nicotinate-nucleotide adenylyltransferase (Deamido-NAD(+) pyrophosphorylase); Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.939 |
| Rta_15950 | nadE | Rta_15950 | Rta_23030 | (NAD(+) diphosphorylase) (NMN adenylyltransferase); ADP compounds hydrolase. | Candidate NAD(+) synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.960 |
| Rta_15950 | pntA | Rta_15950 | Rta_02100 | (NAD(+) diphosphorylase) (NMN adenylyltransferase); ADP compounds hydrolase. | Candidate NAD(P) transhydrogenase subunit alpha part 1. | 0.900 |
| Rta_15950 | pntAb | Rta_15950 | Rta_02110 | (NAD(+) diphosphorylase) (NMN adenylyltransferase); ADP compounds hydrolase. | Candidate NAD(P) transhydrogenase subunit alpha part2. | 0.900 |
| Rta_15950 | pntB | Rta_15950 | Rta_02120 | (NAD(+) diphosphorylase) (NMN adenylyltransferase); ADP compounds hydrolase. | Candidate NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.902 |
| Rta_15950 | ppnK | Rta_15950 | Rta_33190 | (NAD(+) diphosphorylase) (NMN adenylyltransferase); ADP compounds hydrolase. | Candidate inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase); Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.925 |
| Rta_33210 | hrcA | Rta_33210 | Rta_33180 | P-loop-containing kinase-like protein; Displays ATPase and GTPase activities. | Candidate transcriptional regulator HrcA (Heat-inducible transcription repressor hrcA), HrcA family; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.732 |
| Rta_33210 | ppnK | Rta_33210 | Rta_33190 | P-loop-containing kinase-like protein; Displays ATPase and GTPase activities. | Candidate inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase); Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.835 |
| Rta_33210 | recN | Rta_33210 | Rta_33200 | P-loop-containing kinase-like protein; Displays ATPase and GTPase activities. | Candidate DNA repair ATPase; May be involved in recombinational repair of damaged DNA. | 0.856 |
| cobB | Rta_15950 | Rta_19190 | Rta_15950 | NAD-dependent protein deacetylase, SIR2 family-like protein; Belongs to the sirtuin family. Class III subfamily. | (NAD(+) diphosphorylase) (NMN adenylyltransferase); ADP compounds hydrolase. | 0.967 |
| cobB | nadD | Rta_19190 | Rta_21170 | NAD-dependent protein deacetylase, SIR2 family-like protein; Belongs to the sirtuin family. Class III subfamily. | Candidate nicotinate-nucleotide adenylyltransferase (Deamido-NAD(+) pyrophosphorylase); Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.934 |
| cobB | nadE | Rta_19190 | Rta_23030 | NAD-dependent protein deacetylase, SIR2 family-like protein; Belongs to the sirtuin family. Class III subfamily. | Candidate NAD(+) synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.951 |
| cobB | pntA | Rta_19190 | Rta_02100 | NAD-dependent protein deacetylase, SIR2 family-like protein; Belongs to the sirtuin family. Class III subfamily. | Candidate NAD(P) transhydrogenase subunit alpha part 1. | 0.905 |
| cobB | pntAb | Rta_19190 | Rta_02110 | NAD-dependent protein deacetylase, SIR2 family-like protein; Belongs to the sirtuin family. Class III subfamily. | Candidate NAD(P) transhydrogenase subunit alpha part2. | 0.904 |
| cobB | pntB | Rta_19190 | Rta_02120 | NAD-dependent protein deacetylase, SIR2 family-like protein; Belongs to the sirtuin family. Class III subfamily. | Candidate NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.901 |
| cobB | ppnK | Rta_19190 | Rta_33190 | NAD-dependent protein deacetylase, SIR2 family-like protein; Belongs to the sirtuin family. Class III subfamily. | Candidate inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase); Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.916 |
| hrcA | Rta_33210 | Rta_33180 | Rta_33210 | Candidate transcriptional regulator HrcA (Heat-inducible transcription repressor hrcA), HrcA family; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | P-loop-containing kinase-like protein; Displays ATPase and GTPase activities. | 0.732 |
| hrcA | ppnK | Rta_33180 | Rta_33190 | Candidate transcriptional regulator HrcA (Heat-inducible transcription repressor hrcA), HrcA family; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | Candidate inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase); Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.684 |
| hrcA | recN | Rta_33180 | Rta_33200 | Candidate transcriptional regulator HrcA (Heat-inducible transcription repressor hrcA), HrcA family; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | Candidate DNA repair ATPase; May be involved in recombinational repair of damaged DNA. | 0.771 |
