| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rta_33230 | ispE | Rta_33230 | Rta_33270 | Conserved hypothetical protein. | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.505 |
| Rta_33230 | lolB | Rta_33230 | Rta_33260 | Conserved hypothetical protein. | Candidate Outer-membrane lipoprotein lolB precursor; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.600 |
| Rta_33230 | mutM | Rta_33230 | Rta_33240 | Conserved hypothetical protein. | Candidate formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.650 |
| Rta_33230 | mutY | Rta_33230 | Rta_33220 | Conserved hypothetical protein. | Candidate A/G-specific adenine glycosylase protein; Adenine glycosylase active on G-A mispairs. | 0.756 |
| dnaN | metG | Rta_00020 | Rta_30620 | Candidate DNA polymerase III sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required [...] | Candidate methionyl-tRNA synthetase (Methionine--tRNA ligase); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.490 |
| dnaN | mutL | Rta_00020 | Rta_26010 | Candidate DNA polymerase III sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required [...] | Candidate DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.933 |
| dnaN | mutY | Rta_00020 | Rta_33220 | Candidate DNA polymerase III sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required [...] | Candidate A/G-specific adenine glycosylase protein; Adenine glycosylase active on G-A mispairs. | 0.802 |
| dnaN | xthA | Rta_00020 | Rta_14470 | Candidate DNA polymerase III sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required [...] | Candidate exodeoxyribonuclease III. | 0.739 |
| dnaN | xthB | Rta_00020 | Rta_20710 | Candidate DNA polymerase III sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required [...] | Candidate exodeoxyribonuclease III. | 0.739 |
| dnaN | xthC | Rta_00020 | Rta_03890 | Candidate DNA polymerase III sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required [...] | Candidate exodeoxyribonuclease III. | 0.739 |
| ispE | Rta_33230 | Rta_33270 | Rta_33230 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | Conserved hypothetical protein. | 0.505 |
| ispE | lolB | Rta_33270 | Rta_33260 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | Candidate Outer-membrane lipoprotein lolB precursor; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.877 |
| ispE | mutM | Rta_33270 | Rta_33240 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | Candidate formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.649 |
| ispE | mutY | Rta_33270 | Rta_33220 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | Candidate A/G-specific adenine glycosylase protein; Adenine glycosylase active on G-A mispairs. | 0.631 |
| lolB | Rta_33230 | Rta_33260 | Rta_33230 | Candidate Outer-membrane lipoprotein lolB precursor; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Conserved hypothetical protein. | 0.600 |
| lolB | ispE | Rta_33260 | Rta_33270 | Candidate Outer-membrane lipoprotein lolB precursor; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.877 |
| lolB | mutM | Rta_33260 | Rta_33240 | Candidate Outer-membrane lipoprotein lolB precursor; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Candidate formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.642 |
| lolB | mutY | Rta_33260 | Rta_33220 | Candidate Outer-membrane lipoprotein lolB precursor; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Candidate A/G-specific adenine glycosylase protein; Adenine glycosylase active on G-A mispairs. | 0.556 |
| metG | dnaN | Rta_30620 | Rta_00020 | Candidate methionyl-tRNA synthetase (Methionine--tRNA ligase); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Candidate DNA polymerase III sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required [...] | 0.490 |
| metG | mutL | Rta_30620 | Rta_26010 | Candidate methionyl-tRNA synthetase (Methionine--tRNA ligase); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Candidate DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.495 |
