Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ubiACandidate 4-hydroxybenzoate octaprenyltransferase (4-HB polyprenyltransferase); Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (291 aa)    
Predicted Functional Partners:
Rta_32470
Candidate 4-hydroxybenzoyl-CoA thioesterase.
     
 0.901
Rta_29130
Trans-hexaprenyltranstransferase (All-trans-heptaprenyl-diphosphate synthase)-like protein; (Heptaprenyl diphosphate synthase) (Heptaprenyl pyrophosphate synthetase); Belongs to the FPP/GGPP synthase family.
 
 
 0.893
Rta_34300
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase-like protein.
  
   
 0.796
Rta_36250
DNA-binding ferritin-like protein-like protein; Belongs to the Dps family.
       0.792
ubiG
DHHB methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
 
 
 0.759
ubiB
Candidate 2-octaprenylphenol hydroxylase of ubiquinone biosynthetic pathway; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
  
 
 
 0.658
oxyR
Candidate transcriptional regulator OxyR; Hydrogen peroxide-inducible genes activator, LysR family; Belongs to the LysR transcriptional regulatory family.
       0.560
recG
Candidate ATP-dependent DNA helicase recG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
     
 0.555
Rta_30410
Polyketide synthase-like protein.
     
 0.542
ubiE
Candidate Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
 
   
 0.515
Your Current Organism:
Ramlibacter tataouinensis
NCBI taxonomy Id: 365046
Other names: Acidivorax sp. TTB310, Acidovorax sp. TTB310, R. tataouinensis TTB310, Ramlibacter tataouinensis TTB310, Ramlibacter tataouinensis str. TTB310, Ramlibacter tataouinensis strain TTB310
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