node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SIQ45512.1 | SIQ65802.1 | SAMN05421840_101237 | SAMN05421840_10335 | ATP diphosphatase. | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.929 |
SIQ45512.1 | coaE | SAMN05421840_101237 | SAMN05421840_106130 | ATP diphosphatase. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.926 |
SIQ45512.1 | dut | SAMN05421840_101237 | SAMN05421840_10336 | ATP diphosphatase. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.542 |
SIQ65802.1 | SIQ45512.1 | SAMN05421840_10335 | SAMN05421840_101237 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | ATP diphosphatase. | 0.929 |
SIQ65802.1 | SIR13631.1 | SAMN05421840_10335 | SAMN05421840_109133 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.925 |
SIQ65802.1 | SIR17788.1 | SAMN05421840_10335 | SAMN05421840_110120 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Cystathionine beta-lyase. | 0.927 |
SIQ65802.1 | SIR20743.1 | SAMN05421840_10335 | SAMN05421840_111106 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Aspartate aminotransferase. | 0.918 |
SIQ65802.1 | SIR22319.1 | SAMN05421840_10335 | SAMN05421840_11225 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Cysteine synthase A. | 0.925 |
SIQ65802.1 | coaA | SAMN05421840_10335 | SAMN05421840_1303 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase. | 0.936 |
SIQ65802.1 | coaD | SAMN05421840_10335 | SAMN05421840_11657 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.964 |
SIQ65802.1 | coaE | SAMN05421840_10335 | SAMN05421840_106130 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.799 |
SIQ65802.1 | dut | SAMN05421840_10335 | SAMN05421840_10336 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.979 |
SIQ65802.1 | panC | SAMN05421840_10335 | SAMN05421840_10483 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.957 |
SIR13631.1 | SIQ65802.1 | SAMN05421840_109133 | SAMN05421840_10335 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.925 |
SIR13631.1 | SIR17788.1 | SAMN05421840_109133 | SAMN05421840_110120 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Cystathionine beta-lyase. | 0.982 |
SIR13631.1 | SIR20743.1 | SAMN05421840_109133 | SAMN05421840_111106 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Aspartate aminotransferase. | 0.926 |
SIR13631.1 | SIR22319.1 | SAMN05421840_109133 | SAMN05421840_11225 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Cysteine synthase A. | 0.927 |
SIR17788.1 | SIQ65802.1 | SAMN05421840_110120 | SAMN05421840_10335 | Cystathionine beta-lyase. | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.927 |
SIR17788.1 | SIR13631.1 | SAMN05421840_110120 | SAMN05421840_109133 | Cystathionine beta-lyase. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.982 |
SIR17788.1 | SIR20743.1 | SAMN05421840_110120 | SAMN05421840_111106 | Cystathionine beta-lyase. | Aspartate aminotransferase. | 0.925 |