node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SIQ46679.1 | SIQ66398.1 | SAMN05421840_101287 | SAMN05421840_10357 | Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains. | Reactive intermediate/imine deaminase. | 0.588 |
SIQ57988.1 | SIQ66371.1 | SAMN05421840_102215 | SAMN05421840_10356 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase /prephenate dehydratase. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.435 |
SIQ57988.1 | SIQ66398.1 | SAMN05421840_102215 | SAMN05421840_10357 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase /prephenate dehydratase. | Reactive intermediate/imine deaminase. | 0.862 |
SIQ57988.1 | SIR13416.1 | SAMN05421840_102215 | SAMN05421840_109125 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase /prephenate dehydratase. | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.578 |
SIQ57988.1 | fusA | SAMN05421840_102215 | SAMN05421840_104104 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase /prephenate dehydratase. | Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | 0.556 |
SIQ57988.1 | fusA-2 | SAMN05421840_102215 | SAMN05421840_1242 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase /prephenate dehydratase. | Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | 0.556 |
SIQ57988.1 | ilvA | SAMN05421840_102215 | SAMN05421840_11323 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase /prephenate dehydratase. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.581 |
SIQ57988.1 | rpoZ | SAMN05421840_102215 | SAMN05421840_10355 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase /prephenate dehydratase. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.556 |
SIQ66371.1 | SIQ57988.1 | SAMN05421840_10356 | SAMN05421840_102215 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase /prephenate dehydratase. | 0.435 |
SIQ66371.1 | SIQ66398.1 | SAMN05421840_10356 | SAMN05421840_10357 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Reactive intermediate/imine deaminase. | 0.728 |
SIQ66371.1 | gmk | SAMN05421840_10356 | SAMN05421840_10354 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.969 |
SIQ66371.1 | ilvA | SAMN05421840_10356 | SAMN05421840_11323 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.449 |
SIQ66371.1 | rpoZ | SAMN05421840_10356 | SAMN05421840_10355 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.737 |
SIQ66398.1 | SIQ46679.1 | SAMN05421840_10357 | SAMN05421840_101287 | Reactive intermediate/imine deaminase. | Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains. | 0.588 |
SIQ66398.1 | SIQ57988.1 | SAMN05421840_10357 | SAMN05421840_102215 | Reactive intermediate/imine deaminase. | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase /prephenate dehydratase. | 0.862 |
SIQ66398.1 | SIQ66371.1 | SAMN05421840_10357 | SAMN05421840_10356 | Reactive intermediate/imine deaminase. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.728 |
SIQ66398.1 | SIR13416.1 | SAMN05421840_10357 | SAMN05421840_109125 | Reactive intermediate/imine deaminase. | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.635 |
SIQ66398.1 | fusA | SAMN05421840_10357 | SAMN05421840_104104 | Reactive intermediate/imine deaminase. | Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | 0.730 |
SIQ66398.1 | fusA-2 | SAMN05421840_10357 | SAMN05421840_1242 | Reactive intermediate/imine deaminase. | Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | 0.730 |
SIQ66398.1 | gmk | SAMN05421840_10357 | SAMN05421840_10354 | Reactive intermediate/imine deaminase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.650 |