STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIR16421.1CBS domain-containing protein. (138 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.906
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.826
SIQ50752.1
dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
  
 0.818
SIQ49830.1
Flagellar protein FlaG.
    
   0.788
purH
IMP cyclohydrolase.
  
 
 0.680
SIR15898.1
Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
  0.679
SIR42058.1
Arabinose-5-phosphate isomerase.
    
  0.674
SIQ49128.1
Aminotransferase, LLPSF_NHT_00031 family; Belongs to the DegT/DnrJ/EryC1 family.
   
  
 0.672
SIQ50810.1
dTDP-4-amino-4,6-dideoxygalactose transaminase; Belongs to the DegT/DnrJ/EryC1 family.
   
  
 0.672
surE
5'-nucleotidase /3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
   
  0.670
Your Current Organism:
Shewanella morhuae
NCBI taxonomy Id: 365591
Other names: NBRC 100978, S. morhuae, Shewanella morhuae Satomi et al. 2006 emend. Thorell et al. 2019, strain U1417
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