Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_0034Conserved hypothetical protein. (323 aa)    
Predicted Functional Partners:
zmpB
Zinc metalloprotease; LPXTG motif.
  
     0.743
licB
Choline transport protein.
  
     0.730
smi_1306
Surface anchored protein; LPXTG motif.
  
     0.643
pce2
Teichoic acid phosphorylcholine esterase/choline binding protein E, Pce2, truncation; COG2333, ComEC, predicted hydrolase (metallo-beta-lactamase superfamily).
  
    0.576
licA
Choline kinase.
  
     0.547
licC
CTP:phosphocholine cytidylyltransferase.
  
     0.512
prsA
Phosphoribosylpyrophosphate synthase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
       0.504
lytB
endo-beta-N-acetylglucosaminidase LytB; COG5263, glucan-binding domain (YG repeat).
  
     0.486
smi_1060
Conserved hypothetical protein.
  
     0.460
smi_0386
Conserved hypothetical protein.
  
     0.440
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.