comB protein (Streptococcus mitis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

comB

Competence factor transport protein ComB. (449 aa)

Predicted Functional Partners:

comA

0.993

purC

0.779

comE

0.601

salY

0.525

smi_1075

0.525

smi_1459

0.525

spiH

0.507

smi_0675

0.449

smi_0117

0.443

purL

0.432

Your Current Organism:

Streptococcus mitis

NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
comA	comB	smi_0064	smi_0065	Transport ATP-binding protein ComA.	Competence factor transport protein ComB.	0.993
comA	purC	smi_0064	smi_0066	Transport ATP-binding protein ComA.	Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Belongs to the SAICAR synthetase family.	0.746
comA	purL	smi_0064	smi_0067	Transport ATP-binding protein ComA.	Phosphoribosylformylglycinamide synthetase.	0.401
comA	spiH	smi_0064	smi_0366	Transport ATP-binding protein ComA.	Histidine kinase; Peptide pheromone receptor, ComD type.	0.504
comB	comA	smi_0065	smi_0064	Competence factor transport protein ComB.	Transport ATP-binding protein ComA.	0.993
comB	comE	smi_0065	smi_2083	Competence factor transport protein ComB.	Response regulator; comE, competence-specific.	0.601
comB	purC	smi_0065	smi_0066	Competence factor transport protein ComB.	Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Belongs to the SAICAR synthetase family.	0.779
comB	purL	smi_0065	smi_0067	Competence factor transport protein ComB.	Phosphoribosylformylglycinamide synthetase.	0.432
comB	salY	smi_0065	smi_0841	Competence factor transport protein ComB.	ABC transporter, permease; COG0577, ABC-type antimicrobial peptide transport system, permease component.	0.525
comB	smi_0117	smi_0065	smi_0117	Competence factor transport protein ComB.	Conserved hypothetical protein.	0.443
comB	smi_0675	smi_0065	smi_0675	Competence factor transport protein ComB.	Major facilitator superfamily transporter-efflux?.	0.449
comB	smi_1075	smi_0065	smi_1075	Competence factor transport protein ComB.	ABC transporter, membrane-spanning protein; Pfam02687, FtsX, predicted permease.	0.525
comB	smi_1459	smi_0065	smi_1459	Competence factor transport protein ComB.	ABC transporter, permease; ABC-type antimicrobial peptide transport system.	0.525
comB	spiH	smi_0065	smi_0366	Competence factor transport protein ComB.	Histidine kinase; Peptide pheromone receptor, ComD type.	0.507
comE	comB	smi_2083	smi_0065	Response regulator; comE, competence-specific.	Competence factor transport protein ComB.	0.601
comE	spiH	smi_2083	smi_0366	Response regulator; comE, competence-specific.	Histidine kinase; Peptide pheromone receptor, ComD type.	0.891
purC	comA	smi_0066	smi_0064	Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Belongs to the SAICAR synthetase family.	Transport ATP-binding protein ComA.	0.746
purC	comB	smi_0066	smi_0065	Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Belongs to the SAICAR synthetase family.	Competence factor transport protein ComB.	0.779
purC	purL	smi_0066	smi_0067	Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Belongs to the SAICAR synthetase family.	Phosphoribosylformylglycinamide synthetase.	0.981
purL	comA	smi_0067	smi_0064	Phosphoribosylformylglycinamide synthetase.	Transport ATP-binding protein ComA.	0.401