| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| purB | purC | smi_0076 | smi_0066 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | 0.999 |
| purB | purD | smi_0076 | smi_0073 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylglycinamide synthetase; Belongs to the GARS family. | 0.986 |
| purB | purE | smi_0076 | smi_0074 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.998 |
| purB | purF | smi_0076 | smi_0068 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyl transferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.995 |
| purB | purH | smi_0076 | smi_0072 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.998 |
| purB | purK | smi_0076 | smi_0075 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosyl glucinamide formyltransferase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.998 |
| purB | purL | smi_0076 | smi_0067 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamide synthetase. | 0.997 |
| purB | purM | smi_0076 | smi_0069 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamide cyclo-ligase. | 0.995 |
| purB | purN | smi_0076 | smi_0070 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 5'-phosphoribosylglycinamide transformylase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.911 |
| purB | thrB | smi_0076 | smi_0774 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.819 |
| purC | purB | smi_0066 | smi_0076 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.999 |
| purC | purD | smi_0066 | smi_0073 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide synthetase; Belongs to the GARS family. | 0.993 |
| purC | purE | smi_0066 | smi_0074 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
| purC | purF | smi_0066 | smi_0068 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Amidophosphoribosyl transferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.994 |
| purC | purH | smi_0066 | smi_0072 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.995 |
| purC | purK | smi_0066 | smi_0075 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosyl glucinamide formyltransferase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.999 |
| purC | purL | smi_0066 | smi_0067 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamide synthetase. | 0.999 |
| purC | purM | smi_0066 | smi_0069 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamide cyclo-ligase. | 0.999 |
| purC | purN | smi_0066 | smi_0070 | Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | 5'-phosphoribosylglycinamide transformylase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.992 |
| purD | purB | smi_0073 | smi_0076 | Phosphoribosylglycinamide synthetase; Belongs to the GARS family. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.986 |