Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_0078Conserved hypothetical protein. (238 aa)    
Predicted Functional Partners:
PTS-EIIC
PTS system, IIC component.
 
    0.778
bgaC
Beta-galactosidase 3; Belongs to the glycosyl hydrolase 35 family.
 
   
 0.755
PTS-EII
Phosphotransferase system sugar-specific EII component.
 
     0.751
ptsG
PTS glucose-specific enzyme IIABC component.
  
  
 0.744
smi_1615
PTS system; COG1263.
  
  
 0.744
PTS-EIID
PTS system, IID component.
 
    0.733
PTS-EIIB
Phosphotransferase system sugar-specific EIIB component.
 
    0.706
nadR
Bifunctional NadR protein; COG3172, NadR, predicted ATPase/kinase involved in NAD metabolism.
   
    0.670
agaS
Tagatose-6-phosphate ketose/aldose isomerase.
 
  
 0.647
smi_1284
Conserved hypothetical protein; COG4781, Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase.
      
 0.615
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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