Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_0109PTS system, IIB component. (94 aa)    
Predicted Functional Partners:
smi_0110
PTS system, IIC component.
 
 
 0.997
smi_0221
Phosphotransferase system sugar-specific EII component.
 
 
 0.990
smi_0108
Transcriptional regulator, BglG family.
 
  
 0.974
smi_0219
Phosphotransferase system sugar-specific EII component.
 
 
 0.972
smi_0220
Phosphotransferase system sugar-specific EII component.
  
  
  0.932
tktN
Transketolase n-terminal section.
 
    0.909
smi_0226
Conserved hypothetical protein.
  
 
  0.908
tktC
Transketolase c-terminal section.
 
     0.907
ptsH
Phosphocarrier protein HPr.
    
  0.902
smi_0225
Conserved hypothetical protein; Transcriptional regulator, BglG family.
 
     0.755
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.