Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
smi_0125Metal-dependent CAAX amino terminal membrane protease family protein; Pfam02517. (213 aa)    
Predicted Functional Partners:
smi_0124
ABC transporter, ATP-binding protein.
  
    0.832
smi_0123
ABC transporter, ATP-binding protein.
  
    0.774
smi_0122
Conserved hypothetical protein; 5 TM helices predicted.
       0.758
smi_0126
Excreted peptide; Bacteriocin/pheromone -type, double glycine-cleavage motif.
       0.723
smi_0120
Transcriptional regulator.
       0.569
smi_0121
Conserved hypothetical protein.
       0.560
smi_0119
Conserved hypothetical protein.
       0.553
pncP
Metal-dependent CAAX amino terminal membrane protease family protein; Pfam02517.
  
     0.547
smi_0128
Conserved hypothetical protein.
  
    0.465
aspS
aspartyl-tRNA synthetase (aspartate-tRNA ligase); Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
       0.460
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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