Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dapD2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase-related protein; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (232 aa)    
Predicted Functional Partners:
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
 
 0.981
hipO
Similar to several hippurate hydrolases and amino acid amidohydrolases; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
 
  
 0.964
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
 0.910
smi_0145
5-formyltetrahydrofolate cyclo-ligase family protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
       0.748
smi_0146
Conserved hypothetical protein.
       0.748
smi_1687
Aspartate kinase; COG0527; Belongs to the aspartokinase family.
 
  
 0.748
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
  
 0.727
lysA
Diaminopimelate decarboxylase.
  
  
 0.665
pbp1b
Penicillin-binding protein 1b; Authentic stop codon.
  
    0.646
guaA
GMP-synthase; Catalyzes the synthesis of GMP from XMP.
   
  
 0.591
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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