Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hipOSimilar to several hippurate hydrolases and amino acid amidohydrolases; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate. (376 aa)    
Predicted Functional Partners:
dapD
2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase-related protein; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
 
  
 0.964
aspC1
Aspartate aminotransferase.
 
  
 0.923
smi_1943
Deacylase; COG0624, acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase /and related deacylases; peptidase family M20. This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification. Family M20 are glutamate carboxypeptidases.
    
 0.906
smi_0145
5-formyltetrahydrofolate cyclo-ligase family protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
  
    0.858
smi_0146
Conserved hypothetical protein.
       0.854
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
   
 0.738
lysA
Diaminopimelate decarboxylase.
     
 0.614
smi_1687
Aspartate kinase; COG0527; Belongs to the aspartokinase family.
 
   
 0.548
pepQ
X-Pro dipeptidase.
     
 0.542
livH
ABC transporter membrane-spanning permease-branched chain amino acid transport; Belongs to the binding-protein-dependent transport system permease family.
      
 0.531
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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