Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_0192Conserved hypothetical protein; Glutamylcysteine synthetase. (425 aa)    
Predicted Functional Partners:
thrC
Threonine synthase.
       0.722
smi_0194
Multi antimicrobial extrusion (MATE) family transporter.
 
     0.552
smi_1429
ABC transporter, ATP binding domain/permease protein; COG1132, ABC-type multidrug transport system, ATPase and permease components.
  
    0.520
smi_0195
Conserved hypothetical protein; COG0546, phosphatase.
  
    0.512
rpoA
DNA-dependent RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
       0.446
rplQ
50S ribosomal protein L17.
       0.440
smi_0056
Conserved hypothetical protein.
  
     0.426
smi_0286
Conserved hypothetical protein.
  
     0.424
smi_0191
Conserved hypothetical protein.
       0.417
smi_1977
Transcriptional regulator; Cd00093, Helix-turn-helix XRE-family like proteins.
  
     0.413
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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