Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_0226Conserved hypothetical protein. (363 aa)    
Predicted Functional Partners:
smi_0219
Phosphotransferase system sugar-specific EII component.
 
 
 0.991
sgh
Hexulose-6-phosphate synthase (HumpS).
 
  
 0.991
smi_0220
Phosphotransferase system sugar-specific EII component.
 
 
  0.985
smi_0221
Phosphotransferase system sugar-specific EII component.
 
  
  0.972
smi_0110
PTS system, IIC component.
 
 
 0.962
sga
Hexulose-6-phosphate isomerase.
 
   
 0.911
smi_0109
PTS system, IIB component.
  
 
  0.908
smi_0225
Conserved hypothetical protein; Transcriptional regulator, BglG family.
 
     0.753
tktA
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
    0.725
araD
L-ribulose 5-phosphate 4-epimerase.
 
   
 0.704
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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