Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rpmGB50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (50 aa)    
Predicted Functional Partners:
rpsI
30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
  
 
 0.982
rpmF
50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
  
 
 0.962
rplL
50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.
  
 
 0.957
secE
Preprotein translocase secE component, COG0690; Belongs to the SecE/SEC61-gamma family.
  
 
 0.956
rpmB
50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
  
 
 0.942
rpmD
50S ribosomal protein L30.
   
 
 0.938
rpsN
30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
  
 
 0.932
rplX
50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
  
 
 0.932
rpsO
30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
  
 
 0.930
rpsT
30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
   
 
 0.930
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
Server load: low (24%) [HD]