Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
manLPhosphotransferase system, mannose-specific EIIAB. (329 aa)    
Predicted Functional Partners:
PTS-EIID
PTS system, IID component.
 
 0.999
manN
Mannose-specific phosphotransferase system component IID.
 
 0.999
manM
Phosphotransferase system, mannose-specific, component IIC.
 
 0.999
PTS-EIIC
PTS system, IIC component.
 
 0.998
ptsH
Phosphocarrier protein HPr.
  
 0.993
PTS-EII
Phosphotransferase system sugar-specific EII component.
 
 
0.960
pmi
Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family.
 
  
 0.959
smi_1688
Conserved hypothetical protein.
 
   
 0.934
fruA
PTS system, fructose specific IIBC component.
  
  
 0.874
smi_1614
Transcriptional regulator/sugar kinase; COG1940.
    
 0.819
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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