smi_0298 protein (Streptococcus mitis) - STRING interaction network

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Score

smi_0298

Thiamine pyrophosphokinase; COG1564, THI80. (220 aa)

Predicted Functional Partners:

rsgA

0.986

rpe

0.909

adk

0.900

cbf1

0.889

smi_0299

0.865

ksgA

0.856

rnmV

0.741

smi_0293

0.737

purR

0.526

smi_1622

0.485

Your Current Organism:

Streptococcus mitis

NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
adk	rsgA	smi_1884	smi_0296	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Conserved hypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.	0.900
adk	smi_0298	smi_1884	smi_0298	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Thiamine pyrophosphokinase; COG1564, THI80.	0.900
cbf1	ksgA	smi_0300	smi_0295	Cmp-binding factor 1.	Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.	0.856
cbf1	purR	smi_0300	smi_0302	Cmp-binding factor 1.	Repressor of purine biosynthetic genes.	0.461
cbf1	rnmV	smi_0300	smi_0294	Cmp-binding factor 1.	Conserved hypothetical protein; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.	0.821
cbf1	rpe	smi_0300	smi_0297	Cmp-binding factor 1.	Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.	0.869
cbf1	rsgA	smi_0300	smi_0296	Cmp-binding factor 1.	Conserved hypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.	0.856
cbf1	smi_0293	smi_0300	smi_0293	Cmp-binding factor 1.	Conserved hypothetical protein.	0.737
cbf1	smi_0298	smi_0300	smi_0298	Cmp-binding factor 1.	Thiamine pyrophosphokinase; COG1564, THI80.	0.889
cbf1	smi_0299	smi_0300	smi_0299	Cmp-binding factor 1.	Conserved hypothetical protein.	0.865
ksgA	cbf1	smi_0295	smi_0300	Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.	Cmp-binding factor 1.	0.856
ksgA	purR	smi_0295	smi_0302	Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.	Repressor of purine biosynthetic genes.	0.497
ksgA	rnmV	smi_0295	smi_0294	Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.	Conserved hypothetical protein; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.	0.913
ksgA	rpe	smi_0295	smi_0297	Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.	Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.	0.917
ksgA	rsgA	smi_0295	smi_0296	Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.	Conserved hypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.	0.883
ksgA	smi_0293	smi_0295	smi_0293	Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.	Conserved hypothetical protein.	0.801
ksgA	smi_0298	smi_0295	smi_0298	Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.	Thiamine pyrophosphokinase; COG1564, THI80.	0.856
ksgA	smi_0299	smi_0295	smi_0299	Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.	Conserved hypothetical protein.	0.856
purR	cbf1	smi_0302	smi_0300	Repressor of purine biosynthetic genes.	Cmp-binding factor 1.	0.461
purR	ksgA	smi_0302	smi_0295	Repressor of purine biosynthetic genes.	Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.	0.497