Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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[Homology]
Score
lysADiaminopimelate decarboxylase. (416 aa)    
Predicted Functional Partners:
smi_1687
Aspartate kinase; COG0527; Belongs to the aspartokinase family.
 
  
 0.869
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
 0.859
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
   
 0.800
purR
Repressor of purine biosynthetic genes.
  
  
 0.752
guaA
GMP-synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.699
dapD
2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase-related protein; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
  
  
 0.665
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
  
 0.639
pflC
Pyruvate-formate lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
       0.626
thrA
Homoserine dehydrogenase.
 
  
 0.621
hipO
Similar to several hippurate hydrolases and amino acid amidohydrolases; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
     
 0.614
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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