Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
smi_0305ABC transporter, ATP-binding protein. (236 aa)    
Predicted Functional Partners:
smi_0306
ABC transporter, membrane protein.
       0.865
smi_0307
ABC transporter, membrane protein.
       0.847
proV
ABC transporter, ATP-binding protein.
 
   
0.846
smi_0309
Histidine kinase.
   
   0.662
smi_0651
ABC transporter, ATP-binding protein.
  
  0.655
smi_0308
Response regulator.
     
 0.629
smi_0578
ABC exporter ATP binding/membrane-spanning protein, drug efflux; COG1132.
  
  0.628
smi_0257
Conserved hypothetical protein; ABC transporter permease protein.
 
    0.438
smi_0958
Conserved hypothetical protein.
  
 
 0.433
pflC
Pyruvate-formate lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
  
    0.415
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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