Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
smi_0327ABC transporter, substrate binding protein; COG2984, ABC-type transport system. (325 aa)    
Predicted Functional Partners:
smi_0328
ABC-type transport system, permease component; COG 4120; Belongs to the binding-protein-dependent transport system permease family.
    0.995
smi_0989
COG4120, ABC-type uncharacterized transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.
    0.967
smi_0329
ABC-type uncharacterized transport system, ATPase component COG1101.
 
    0.966
smi_0990
ABC transporter, ATP-binding protein; COG1101, ABC-type uncharacterized transport system, ATPase component.
 
    0.809
smi_0330
Dextran glucosidase, truncation.
       0.692
smi_0331
Conserved hypothetical protein.
       0.438
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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