Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
smi_0360Conserved hypothetical protein; HIT family protein. (136 aa)    
Predicted Functional Partners:
smi_0359
Conserved hypothetical protein.
       0.865
smi_0362
ABC transporter membrane-spanning permease.
     
 0.816
smi_0361
This family of ATP-binding proteins belongs to a multisubunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins.
  
  
 0.624
glnA
Glutamine synthetase type 1.
  
   0.514
smi_0880
Conserved hypothetical protein.
  
 
  0.476
smi_0378
L7A family ribosomal protein; Pfam01248.
 
    0.472
cotS
Aminoglycoside phosphotransferase.
       0.461
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
       0.461
nusA
Transcription termination-antitermination factor; Participates in both transcription termination and antitermination.
       0.409
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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