Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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trmBtRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (211 aa)    
Predicted Functional Partners:
rimP
Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
     
 0.890
cotS
Aminoglycoside phosphotransferase.
       0.865
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
 
 0.848
smi_1624
rRNA-specific 5-methylcytidine transferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
 
 0.723
smi_0378
L7A family ribosomal protein; Pfam01248.
  
   0.712
IF2
Translation initiation factor; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
  
   0.706
nusA
Transcription termination-antitermination factor; Participates in both transcription termination and antitermination.
       0.668
smi_0731
Conserved hypothetical protein; COG0144, sun, tRNA and rRNA cytosine-C5-methylases [.
  
 
 0.652
smi_0377
Nucleic-acid-binding protein implicated in transcription termination.
       0.651
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
  
 
 0.640
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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