Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
smi_0387Acetyltransferase, GNAT family; COG1670, RimL, acetyltransferases, including N-acetylases of ribosomal proteins. (186 aa)    
Predicted Functional Partners:
smi_0388
COG0703, shikimate kinase.
 
     0.804
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
  
    0.779
smi_0386
Conserved hypothetical protein.
       0.777
mutT
Mutator mutT protein; 7,8-dihydro-8-oxoguanine-triphosphatase; 8-oxo-dGTPase; dGTP pyrophosphohydrolase; Belongs to the Nudix hydrolase family.
 
 
    0.643
ddeI
Type II DNA modification enzyme (methyltransferase cytosine-specific).
       0.563
smi_0392
Hypothetical protein.
  
    0.555
smi_0391
COG0326, molecular chaperone, HSP90 family.
       0.545
smi_0385
Helicase; COG1204, superfamily II helicase.
       0.422
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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