Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
smi_0394DNA or RNA helicases of superfamily II; COG1061. (892 aa)    
Predicted Functional Partners:
dinG
ATP-dependent helicase DinG; 3'-5' exonuclease.
   
 0.857
rpoA
DNA-dependent RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.768
rpoB
DNA-dependent RNA Polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.740
smi_0395
Conserved hypothetical protein truncation.
       0.721
polI
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.698
rpoZ
DNA-dependent RNA Polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
  0.683
rpoC
DNA-dependent RNA Polymerase, beta-prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.484
smi_0393
Cell filamentation protein Fic-related protein; COG2184.
       0.478
smi_0396
Transcriptional regulator, TetR family.
       0.465
smi_0397
ABC transporter, ATP-binding protein.
       0.465
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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