Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
smi_0488tRNA methyltransferase, TrmA family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (440 aa)    
Predicted Functional Partners:
recX
Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family.
 
    0.786
smi_0486
Uncharacterized domain/protein associated with RNAses G and E; COG3557; Belongs to the UPF0374 family.
       0.668
smi_0754
Conserved hypothetical protein.
  
  
 0.597
smi_1752
DNA methylase; COG0116, predicted N6-adenine-specific DNA methylase; Belongs to the methyltransferase superfamily.
   
  
 0.597
smi_0283
Conserved hypothetical protein.
       0.461
smi_1935
NrdI family protein; COG1780, proteins involved in ribonucleotide reduction; Belongs to the NrdI family.
       0.460
pheT
phenylalanyl-tRNA synthetase, beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
  
 0.410
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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