Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
smi_0533Conserved hypothetical protein; COG5658, predicted integral membrane protein, lipoprotein signature. (213 aa)    
Predicted Functional Partners:
smi_0532
Transcriptional regulator, ArsR family; COG0640.
 
  
 0.984
smi_0531
Metal-dependent membrane protease, CAAX amino terminal protease family protein; COG1266.
 
     0.905
exoA
Exodeoxyribonuclease III.
       0.703
smi_0534
Conserved hypothetical protein.
       0.496
smi_0535
Conserved hypothetical protein; COG2323.
       0.496
smi_0529
Conserved hypothetical protein.
       0.473
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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