Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_0534Conserved hypothetical protein. (151 aa)    
Predicted Functional Partners:
smi_0535
Conserved hypothetical protein; COG2323.
 
    0.953
exoA
Exodeoxyribonuclease III.
       0.608
smi_0862
Acetyltransferase; Pfam00583, Acetyltransf_1, acetyltransferase (GNAT) family.
  
     0.567
smi_0531
Metal-dependent membrane protease, CAAX amino terminal protease family protein; COG1266.
 
     0.554
smi_0124
ABC transporter, ATP-binding protein.
  
     0.545
smi_0536
ABC transporter, ATP-binding domain/permease protein, lipid/multidrug/protein-type ABC exporter; MsbA is an ABC transporter, closely related to eukaryotic MDR proteins.
       0.510
smi_0537
ABC transporter, ATP-binding domain/permease protein, lipid/multidrug/protein-type ABC exporter.
       0.498
smi_0532
Transcriptional regulator, ArsR family; COG0640.
       0.496
smi_0533
Conserved hypothetical protein; COG5658, predicted integral membrane protein, lipoprotein signature.
       0.496
smi_0529
Conserved hypothetical protein.
 
     0.493
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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