| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fruA | ptsG | smi_1357 | smi_1404 | PTS system, fructose specific IIBC component. | PTS glucose-specific enzyme IIABC component. | 0.983 |
| fruA | smi_0555 | smi_1357 | smi_0555 | PTS system, fructose specific IIBC component. | Transcriptional activator, Mga-like regulatory protein; Pfam05043, Mga, M protein trans-acting positive regulator (MGA). Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. | 0.582 |
| fruA | smi_1615 | smi_1357 | smi_1615 | PTS system, fructose specific IIBC component. | PTS system; COG1263. | 0.987 |
| ptsG | fruA | smi_1404 | smi_1357 | PTS glucose-specific enzyme IIABC component. | PTS system, fructose specific IIBC component. | 0.983 |
| ptsG | smi_0555 | smi_1404 | smi_0555 | PTS glucose-specific enzyme IIABC component. | Transcriptional activator, Mga-like regulatory protein; Pfam05043, Mga, M protein trans-acting positive regulator (MGA). Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. | 0.636 |
| ptsG | smi_1615 | smi_1404 | smi_1615 | PTS glucose-specific enzyme IIABC component. | PTS system; COG1263. | 0.996 |
| rggD | smi_0555 | smi_0485 | smi_0555 | Transcriptional regulators, MutR family; COG1396. | Transcriptional activator, Mga-like regulatory protein; Pfam05043, Mga, M protein trans-acting positive regulator (MGA). Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. | 0.439 |
| smi_0345 | smi_0555 | smi_0345 | smi_0555 | endo-beta-N-acetylglucosaminidase D; LPXTG motif. | Transcriptional activator, Mga-like regulatory protein; Pfam05043, Mga, M protein trans-acting positive regulator (MGA). Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. | 0.563 |
| smi_0554 | smi_0555 | smi_0554 | smi_0555 | Conserved hypothetical protein. | Transcriptional activator, Mga-like regulatory protein; Pfam05043, Mga, M protein trans-acting positive regulator (MGA). Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. | 0.496 |
| smi_0555 | fruA | smi_0555 | smi_1357 | Transcriptional activator, Mga-like regulatory protein; Pfam05043, Mga, M protein trans-acting positive regulator (MGA). Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. | PTS system, fructose specific IIBC component. | 0.582 |
| smi_0555 | ptsG | smi_0555 | smi_1404 | Transcriptional activator, Mga-like regulatory protein; Pfam05043, Mga, M protein trans-acting positive regulator (MGA). Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. | PTS glucose-specific enzyme IIABC component. | 0.636 |
| smi_0555 | rggD | smi_0555 | smi_0485 | Transcriptional activator, Mga-like regulatory protein; Pfam05043, Mga, M protein trans-acting positive regulator (MGA). Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. | Transcriptional regulators, MutR family; COG1396. | 0.439 |
| smi_0555 | smi_0345 | smi_0555 | smi_0345 | Transcriptional activator, Mga-like regulatory protein; Pfam05043, Mga, M protein trans-acting positive regulator (MGA). Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. | endo-beta-N-acetylglucosaminidase D; LPXTG motif. | 0.563 |
| smi_0555 | smi_0554 | smi_0555 | smi_0554 | Transcriptional activator, Mga-like regulatory protein; Pfam05043, Mga, M protein trans-acting positive regulator (MGA). Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. | Conserved hypothetical protein. | 0.496 |
| smi_0555 | smi_1538 | smi_0555 | smi_1538 | Transcriptional activator, Mga-like regulatory protein; Pfam05043, Mga, M protein trans-acting positive regulator (MGA). Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. | Cell wall surface anchor family protein; LPXTG motif. | 0.582 |
| smi_0555 | smi_1615 | smi_0555 | smi_1615 | Transcriptional activator, Mga-like regulatory protein; Pfam05043, Mga, M protein trans-acting positive regulator (MGA). Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. | PTS system; COG1263. | 0.636 |
| smi_1538 | smi_0555 | smi_1538 | smi_0555 | Cell wall surface anchor family protein; LPXTG motif. | Transcriptional activator, Mga-like regulatory protein; Pfam05043, Mga, M protein trans-acting positive regulator (MGA). Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. | 0.582 |
| smi_1615 | fruA | smi_1615 | smi_1357 | PTS system; COG1263. | PTS system, fructose specific IIBC component. | 0.987 |
| smi_1615 | ptsG | smi_1615 | smi_1404 | PTS system; COG1263. | PTS glucose-specific enzyme IIABC component. | 0.996 |
| smi_1615 | smi_0555 | smi_1615 | smi_0555 | PTS system; COG1263. | Transcriptional activator, Mga-like regulatory protein; Pfam05043, Mga, M protein trans-acting positive regulator (MGA). Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. | 0.636 |