Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
smi_0555Transcriptional activator, Mga-like regulatory protein; Pfam05043, Mga, M protein trans-acting positive regulator (MGA). Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. (492 aa)    
Predicted Functional Partners:
ptsG
PTS glucose-specific enzyme IIABC component.
  
 
 0.636
smi_1615
PTS system; COG1263.
  
 
 0.636
fruA
PTS system, fructose specific IIBC component.
  
  
 0.582
smi_1538
Cell wall surface anchor family protein; LPXTG motif.
  
     0.582
smi_0345
endo-beta-N-acetylglucosaminidase D; LPXTG motif.
  
     0.563
smi_0554
Conserved hypothetical protein.
 
     0.496
rggD
Transcriptional regulators, MutR family; COG1396.
  
    0.439
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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