Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_0558Transcriptional regulator; COG1959. (143 aa)    
Predicted Functional Partners:
smi_0557
NADPH:quinone reductase and related Zn-dependent oxidoreductases; COG0604.
 
     0.800
smi_1185
Aminotransferase; COG1104, cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.
  
  
 0.491
smi_1354
Pyridoxal-phosphate dependent aminotransferase; COG1104, cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.
  
  
 0.491
smi_0918
NifU family protein.
  
  
 0.465
smi_0556
Conserved hypothetical protein, truncation.
       0.456
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
Server load: medium (52%) [HD]