Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_0561Conserved hypothetical protein. (156 aa)    
Predicted Functional Partners:
smi_0562
7,8-dihydro-8-oxoguanine-triphosphatase.
       0.865
smi_0564
Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
     
 0.833
prmA
Ribosomal protein methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.
     
 0.806
smi_0560
Chromosome segregation helicase, ATPase, AAA family.
       0.736
sagA
General stress protein GSP-781 amidase; Pfam05257, CHAP domain. This domain corresponds to an amidase function.
  
     0.683
smi_1287
Conserved hypothetical protein.
  
     0.641
smi_0864
Conserved hypothetical protein; Pfam00293, NUDIX; COG0494, MutT; Belongs to the Nudix hydrolase family.
  
     0.629
smi_0008
Conserved hypothetical protein.
  
     0.618
smi_1186
Conserved hypothetical protein.
  
     0.570
smi_1292
Lysozyme; COG3757, lyzozyme M1 (1,4-beta-N-acetylmuramidase).
  
     0.562
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
Server load: medium (48%) [HD]