Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
smi_0565Similar to oligoendopeptidase, oligoendopeptidase F; COG1164. (598 aa)    
Predicted Functional Partners:
prmA
Ribosomal protein methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.
       0.856
smi_0564
Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
       0.856
pepP
COG0006, Xaa-Pro aminopeptidase; Belongs to the peptidase M24B family.
      
 0.617
pepQ
X-Pro dipeptidase.
      
 0.561
smi_1577
Peptidase M20 superfamily.
     
 0.558
smi_0562
7,8-dihydro-8-oxoguanine-triphosphatase.
       0.545
smi_0561
Conserved hypothetical protein.
       0.543
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.512
pepT
Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
   
  
 0.465
gpo
Gluthatione peroxidase; COG0386; Belongs to the glutathione peroxidase family.
       0.461
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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