Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
smi_0598Conserved hypothetical protein. (308 aa)    
Predicted Functional Partners:
zmpB
Zinc metalloprotease; LPXTG motif.
  
     0.758
licB
Choline transport protein.
  
     0.739
smi_1306
Surface anchored protein; LPXTG motif.
  
     0.678
pce2
Teichoic acid phosphorylcholine esterase/choline binding protein E, Pce2, truncation; COG2333, ComEC, predicted hydrolase (metallo-beta-lactamase superfamily).
  
    0.657
licA
Choline kinase.
  
     0.571
smi_0398
ABC transporter permease protein; COG0577.
  
     0.547
licC
CTP:phosphocholine cytidylyltransferase.
  
     0.532
lytB
endo-beta-N-acetylglucosaminidase LytB; COG5263, glucan-binding domain (YG repeat).
  
     0.515
smi_1060
Conserved hypothetical protein.
  
     0.505
smi_0599
Conserved hypothetical protein; COG1670, acetyltransferase, GNAT family.
       0.484
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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