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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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[Homology]
Score
smi_0668UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (339 aa)    
Predicted Functional Partners:
galT
Galactose-1-phosphate uridylyltransferase.
  
 
 0.984
galU
UTP-glucose-1-phosphate uridylyltransferase.
    
 0.973
galK
Galactokinase, (galactose kinase); Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
  
 
 0.955
glf
UDP-galactopyranose mutase.
    
 0.912
galE
UDP-galactose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
  
  
 
0.911
gcaD
UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
   
 0.878
smi_0669
COG0463, glycosyltransferases involved in cell wall biogenesis.
  
    0.862
lacC
Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
      
 0.703
galR
Member of GalR-LacI family of transcriptional regulators, binds DNA; regulator of gal operon, galactose operon repressor.
  
 
 0.669
smi_0665
Conserved hypothetical protein.
       0.625
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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