smi_0678 protein (Streptococcus mitis) - STRING interaction network

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[Homology]

Score

smi_0678

Conserved hypothetical protein. (153 aa)

Predicted Functional Partners:

smi_0677

0.908

ecfA

0.898

truA

0.865

ecfT

0.863

ecfA-2

0.832

cbiQ

0.819

smi_1483

0.790

smi_1807

0.534

smi_0675

0.526

dnaJ

0.461

Your Current Organism:

Streptococcus mitis

NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cbiQ	ecfA	smi_1809	smi_2067	ABC transporter permease; COG0619, CbiQ, ABC-type cobalt transport system.	ABC transporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	0.989
cbiQ	ecfA-2	smi_1809	smi_2068	ABC transporter permease; COG0619, CbiQ, ABC-type cobalt transport system.	ABCtransporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	0.990
cbiQ	ecfT	smi_1809	smi_2066	ABC transporter permease; COG0619, CbiQ, ABC-type cobalt transport system.	ABC transporter permease, cobalt transport; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	0.909
cbiQ	smi_0678	smi_1809	smi_0678	ABC transporter permease; COG0619, CbiQ, ABC-type cobalt transport system.	Conserved hypothetical protein.	0.819
cbiQ	truA	smi_1809	smi_0676	ABC transporter permease; COG0619, CbiQ, ABC-type cobalt transport system.	tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.	0.601
dnaJ	smi_0677	smi_0357	smi_0677	dnaJ protein, Heat-shock protein (activation of DnaK); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depende [...]	Phosphomethylpyrimidine kinase.	0.506
dnaJ	smi_0678	smi_0357	smi_0678	dnaJ protein, Heat-shock protein (activation of DnaK); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depende [...]	Conserved hypothetical protein.	0.461
dnaJ	smi_1483	smi_0357	smi_1483	dnaJ protein, Heat-shock protein (activation of DnaK); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depende [...]	Conserved hypothetical protein; Belongs to the UPF0340 family.	0.441
dnaJ	truA	smi_0357	smi_0676	dnaJ protein, Heat-shock protein (activation of DnaK); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depende [...]	tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.	0.623
ecfA	cbiQ	smi_2067	smi_1809	ABC transporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	ABC transporter permease; COG0619, CbiQ, ABC-type cobalt transport system.	0.989
ecfA	ecfA-2	smi_2067	smi_2068	ABC transporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	ABCtransporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	0.999
ecfA	ecfT	smi_2067	smi_2066	ABC transporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	ABC transporter permease, cobalt transport; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	0.999
ecfA	smi_0678	smi_2067	smi_0678	ABC transporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	Conserved hypothetical protein.	0.898
ecfA	smi_1807	smi_2067	smi_1807	ABC transporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	Conserved hypothetical protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.	0.614
ecfA	truA	smi_2067	smi_0676	ABC transporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.	0.682
ecfA-2	cbiQ	smi_2068	smi_1809	ABCtransporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	ABC transporter permease; COG0619, CbiQ, ABC-type cobalt transport system.	0.990
ecfA-2	ecfA	smi_2068	smi_2067	ABCtransporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	ABC transporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	0.999
ecfA-2	ecfT	smi_2068	smi_2066	ABCtransporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	ABC transporter permease, cobalt transport; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	0.999
ecfA-2	smi_0678	smi_2068	smi_0678	ABCtransporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	Conserved hypothetical protein.	0.832
ecfA-2	smi_1807	smi_2068	smi_1807	ABCtransporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	Conserved hypothetical protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.	0.655