nagB protein (Streptococcus mitis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

nagB

N-acetylglucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (235 aa)

Predicted Functional Partners:

nagA

0.998

glmM

0.963

glmS

0.961

gpi

0.957

pmi

0.949

smi_1614

0.907

smi_1615

0.892

ptsG

0.860

manL

0.795

fruB

0.733

Your Current Organism:

Streptococcus mitis

NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
fruB	nagB	smi_1358	smi_0714	Fructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.	N-acetylglucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.	0.733
fruB	ptsG	smi_1358	smi_1404	Fructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.	PTS glucose-specific enzyme IIABC component.	0.626
fruB	smi_1614	smi_1358	smi_1614	Fructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.	Transcriptional regulator/sugar kinase; COG1940.	0.609
fruB	smi_1615	smi_1358	smi_1615	Fructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.	PTS system; COG1263.	0.778
glmM	glmS	smi_1550	smi_1850	Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.	Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	0.975
glmM	gpi	smi_1550	smi_0157	Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.499
glmM	nagA	smi_1550	smi_0202	Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.	N-acetylglucosamine-6-phosphate deacetylase.	0.951
glmM	nagB	smi_1550	smi_0714	Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.	N-acetylglucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.	0.963
glmM	pmi	smi_1550	smi_1427	Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.	Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family.	0.523
glmM	ptsG	smi_1550	smi_1404	Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.	PTS glucose-specific enzyme IIABC component.	0.448
glmM	smi_1615	smi_1550	smi_1615	Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.	PTS system; COG1263.	0.448
glmS	glmM	smi_1850	smi_1550	Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.	0.975
glmS	gpi	smi_1850	smi_0157	Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.945
glmS	manL	smi_1850	smi_0274	Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	Phosphotransferase system, mannose-specific EIIAB.	0.472
glmS	nagA	smi_1850	smi_0202	Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	N-acetylglucosamine-6-phosphate deacetylase.	0.967
glmS	nagB	smi_1850	smi_0714	Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	N-acetylglucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.	0.961
glmS	pmi	smi_1850	smi_1427	Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family.	0.931
glmS	ptsG	smi_1850	smi_1404	Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	PTS glucose-specific enzyme IIABC component.	0.562
glmS	smi_1614	smi_1850	smi_1614	Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	Transcriptional regulator/sugar kinase; COG1940.	0.907
glmS	smi_1615	smi_1850	smi_1615	Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	PTS system; COG1263.	0.562

page 1 of 5

Server load: medium (42%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Co-occurrence

Textmining

Co-expression

© STRING Consortium 2026

Credits

Access

Info

About