Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
licD3Phosphorylcholine transferase LicD3; Pfam04991. (281 aa)    
Predicted Functional Partners:
smi_0769
Pfam00535, glycosyl transferase group 2.
 
  
 0.991
licB
Choline transport protein.
 
   
 0.882
smi_0770
Conserved hypothetical protein.
     
 0.829
smi_0768
COG0438, RfaG; pfam00534, glycosyl transferases group 1.
     
 0.828
smi_0771
Conserved hypothetical protein.
     
 0.799
tarJ
Alcohol dehydrogenase; Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate; Belongs to the zinc-containing alcohol dehydrogenase family.
 
   
 0.746
tacF
Teichoic acid subunit flippase; COG2244, Membrane protein involved in the export of O-antigen and teichoic acid.
 
   
 0.737
cbp12
Choline binding protein cbp12; COG5263, glucan-binding domain (YG repeat).
  
   
 0.717
licC
CTP:phosphocholine cytidylyltransferase.
 
   
 0.709
cbp7
Choline binding protein Cbp7; COG5263, glucan binding domain (YG repeat).
  
     0.701
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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